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ACTIVE PULMONARY TUBERCULOSIS DURING INTERFERON BETA-1A THERAPY IN A CHILD WITH MULTIPLE SCLEROSIS: A CASE REPORT
PAKZE CENNETOLU, ZEYNEP Z, CANAN CAYMAZ, PEREN PERK YCEL, PINAR ARICAN, HSAN KAFADAR
Cam and Sakura Medical Journal - 2023;3(3):116-119
University of Health Sciences Turkey, Baakehir am and Sakura City Hospital, Clinic of Pediatrics, Division of Pediatric Neurology, stanbul, Turkey

Interferon (IFN) beta (β) is a potent anti-inflammatory and immunomodulatory agent that is used for treating patients with multiple sclerosis (MS). In this study, we present the case of a 15-year-old female patient diagnosed with MS and treated with IFN β-1a for six months who was referred to the emergency department with complaints of fatigue, fever, and coughing. She was diagnosed with pulmonary tuberculosis (TB). IFN β-1a therapy was stopped and anti-TB treatment was initiated. After nine months of therapy, she recovered from TB. This case presented with a rare side effect during the treatment of pediatric-onset MS with immunomodulatory drugs, demonstrating the importance of screening and close follow-up of patients with TB.

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