« Geri
EXAMINING PRODROME SYMPTOMS OF BIPOLAR DISORDER IN YOUNG ADULT PATIENTS WITH OBSESSIVE COMPULSIVE DISORDER
Mine Ozdem, Mehmet Yumru
Klinik Psikiyatri Dergisi - 2025;28(3):201-210
Ankara University, The Graduate School of Social Sciences, Department of Clinical Psychology

Objective: Obsessive-Compulsive Disorder (OCD) and Bipolar Disorder (BD) frequently co-occur. While several studies suggest a temporal and clinical relationship between the two disorders, little is known about the presence of prodrome BD symptoms in individuals with OCD. This study aimed to examine whether young adults diagnosed with OCD exhibit elevated levels of prodrome symptoms of BD compared to psychiatrically healthy controls. Method: A total of 66 participants aged 18-25 were included: 31 with a diagnosis of OCD and 35 healthy controls. Bipolar prodrome symptoms were assessed using Bipolar Prodrome Symptom Scale (BPSS). Yale-Brown Obsessive Compulsive Scale (Y-BOCS), Hamilton Depression Rating Scale (HDRS), and Young Mania Rating Scale (YMRS) were also administered. Group differences were analyzed using Mann-Whitney U test; associations between OCD severity and prodromal symptoms were examined using Spearman correlation. Results: OCD participants demonstrated significantly higher scores on both the frequency (U = 251.50, p <.001, rrb =.60) and severity (U = 203.50, p <.001, rrb =.62) subscales of BPSS compared to control group. In the total sample, OCD symptom severity was moderately correlated with BPSS severity (r =.58, p <.001) and frequency (r =.53, p <.001). However, within the OCD group alone, these correlations did not reach statistical significance. When Expectation Maximization correction was applied, similar association patterns were observed. Discussion: This is one of the first studies in the literature investigating BD prodrome symptoms in young adult OCD patients. Young adults with OCD exhibit elevated levels of bipolar prodrome symptoms relative to healthy individuals. The absence of within-group correlations and the cross-sectional design limit causal interpretation. Clinicians should consider monitoring prodrome bipolar symptoms in OCD patients, particularly during the late adolescent and early adult years. Future studies with larger sample sizes are needed to confirm the reliability and validity of the findings.

Facebook'ta Payla