Background: Intermittent Explosive Disorder (IED) is an impulse-control disorder characterized by the inability to control emotions and behaviors, resulting in behaviors that violate social norms and the rights of others. The IED Screening Questionnaire (IED-SQ) is a valuable tool that can quickly identify the presence of IED in adults by Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) criteria. This study evaluated a form of the IED-SQ that had been translated into Turkish, and investigated the reliability and validity of the Turkish version of the IED-SQ. Methods: Seventy-one adult IED patients and 68 adult controls participated. The Barratt Impulsivity Scale (BIS-11), Minnesota Impulse Control Disorder Interview Scale (MIDI), Buss Perry Aggression Questionnaire (BPAQ), Symptom Checklist 90-Revised (SCL-90-R), Wender Utah Rating Scale (WURS), and IED-SQ were administered to the participants. Results: The Cronbach’s α coefficient of the IED-SQ was 0.74. The subscales of the BPAQ, including physical aggression, verbal aggression, hostility, and anger, along with the attention and non-planning impulsivity subscales of the BIS-11, were incorporated into the multivariate analysis to identify factors independently associated with the IED-SQ. According to the model, the correct classification percentage was found to be 95%. Conclusions: This study demonstrated that the Turkish version of the IED-SQ is valid and reliable and can be used in clinical practices to identify the presence of IED.