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EXAMINATION OF PERINATAL AND POSTNATAL OUTCOMES OF PREGNANT WOMEN WHO REFUSE THE RECOMMENDED INVASIVE PROCEDURE FOR INCREASED NUCHAL TRANSLUCENCY
LKN SEDA CAN ALAYAN, VLDAN KILI
Perinatal Journal - 2024;32(2):155-160

OBJECTIVE The aim of our study was to detect an increase in nuchal translucency (NT) measurement among our patients attending our clinic for 11-14 weeks of control and to examine the perinatal and postnatal outcomes of pregnant women who were recommended an invasive fetal procedure but refused it. METHODS 107 pregnant women between 11-14 weeks of gestation who were evaluated in our center from 2018 to 2021 and who rejected invasive procedures were included. Patients opting for follow-up and delivery at another facility were excluded from the study. The study groups were categorized into 3 groups based on NT values, regardless of gestational age: 1st Group 2.5-3.4 mm, 2nd Group 3.5-4.5 mm, and 3rd Group>4.5 mm. Fetal ultrasound scans were conducted during the antenatal period, with detailed examinations postnatally. RESULTS Abnormal ultrasound findings were detected in 11.2% of fetuses, with a higher prevalence in groups exhibiting greater NT increases. While chromosomal anomaly was seen in 13% of all fetuses, Group 2 (NT 3.5-4.5mm) had the highest percentage (33.3%). The highest right and healthy birth rates were found in group 1 (91.8%), inversely proportional to the increase in NT. CONCLUSION Increased NT values appear to be associated with increased rates of structural anomalies and adverse perinatal outcomes. Although chromosomal anomalies are associated with NT increase, a direct proportional relationship between the two remains undetermined.

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