Objective: In this study, we aimed to determine the clinical experiences and preferences of Turkish psychiatrists regarding rapid tranquilization of acutely agitated individuals and to evaluate the variables affecting these approaches. Method: A cross-sectional online survey was conducted between November 2019 and March 2020. The survey link was mailed to a sample of 131 Turkish psychiatrists. A significant proportion of the study sample worked in academic institutions like universities. The questionnaire consisted of mostly single-choice questions about rapid tranquilization, the use of zuclopenthixol acetate, and experiences with intravenous haloperidol. Results: Only 34.4% of the clinicians adhered to a guideline and almost half of the clinicians did not follow up with the patients after the rapid tranquilization. Intramuscular drug administration was preferred to a greater extent, and haloperidol was the most preferred first-line agent. Simultaneous anticholinergic administration was an almost established practice. The most preferred use of zuclopenthixol acetate was sedation whereas intravenous haloperidol was applied most frequently for delirium. Discussion: In Turkey, mental health resources are still limited. Moreover, some pharmacological agents or different administration forms are not available. These difficulties seem to increase improper use of rapid tranquilization approaches. A national consensus text is needed and clinicians should be invited to periodic courses. Since the study’s sample tends to be clustered in certain institutions, the findings should be evaluated with caution refraining from overgeneralization.