Objectives: This study aimed to determine the relationship between quality of life and health literacy in individuals presenting to primary health-care institutions. Methods: The study was carried out with a descriptive cross-sectional design between March 5, 2022, and December 20, 2022. The study was completed with 800 individuals (n=800) who presented to An Community Health Center. Descriptive statistics, independent-sample t-tests, analysis of variance, and correlation analyses were used to analyze the data. Data were collected using a descriptive characteristics form, the Turkish Health Literacy Scale, and the World Health Organization Quality of Life Instrument-Short Form. Results: A significant and positive correlation between health literacy and quality of life was identified among individuals who presented to primary health-care institutions (p<0.05). Moreover, it was found that health literacy explained 46% of the variance in quality of life, indicating its strong impact. Conclusion: In the study, it was determined that the health literacy of the participants was at a sufficient level, and their quality of life was moderate. It was observed that an increase in health literacy led to an improvement in quality of life.
