Objectives: This paper investigated the effect of parental attitudes on alexithymia in children with chronic diseases. Methods: This cross-sectional study was conducted at the pediatric outpatient clinics of a state hospital in the southern and central regions of Turkey. The study population consisted of 256 children with chronic diseases. Data were collected using a personal information form, the parental attitudes scale (PAS), and the alexithymia questionnaire for children (AQC). The data were analyzed using a t-test, analysis of variance, and logistic regression. All stages of the study adhered to ethical principles. Results: Participants had a mean AQC score of 20.07±5.83. They had a mean PAS “strictness/supervision,” “acceptance/ involvement,” and “psychological autonomy” subscale score of 30.75±2.55, 28.03±3.89, and 21.13±4.09, respectively. The PAS “acceptance/involvement” subscale score was negatively correlated with the AQC total score and “difficulty identifying feelings” and “difficulty describing feelings” subscale scores (p