Stress, a natural response to challenges, can improve focus and survival instincts, but if excessive or prolonged, it can impair learning, memory, and planning, leading to health issues and exacerbating anxiety and other psychological conditions. When demands exceed coping abilities, individuals feel stressed and experience negative emotions. Events affect individuals based on their evaluation of stress.[1] How individuals interpret their relationship with the environment is crucial in stress perception.[2] Thus, perceiving a situation as stressful and struggling to cope may, in turn, lead to anxiety. Perceived stress and negative emotions, like anxiety, can exacerbate each other, impacting cognitive and emotional equilibrium. [3] Individuals commonly encounter a sense of time distortion when exposed to negative or unpleasant stimuli through various sensory channels.[4] Kramer et al.[5] have shown that meditation can alter time perception. Meditation, particularly mindfulness practices, sensitizes individuals to time and prolongs their perception of it.[6] During meditation, directing attention to the present moment and the breath is thought to facilitate the observation of experiencing uncertainty, implying an acknowledgment and contemplation of uncertainty as well. Intolerance of uncertainty describes individuals' tendency to harbor unacceptable thoughts about potential events, irrespective of their probability.[7] This trait may, in turn, be associated with increased levels of worry, mood anxiety, and the development of anxiety disorders.[8] Individuals with low tolerance for uncertainty perceive it as a threat because they struggle to take precautions, ultimately adding to their stress levels.[7] Hence, it can be inferred that both perceived stress and uncertainty are linked to different levels of anxiety. Anxiety manifests as a complex blend of fear and apprehension that can be challenging to pinpoint,[9] often accompanied by physiological reactions. Anxiety disorders entail intense anxiety, fear, and disruptions in behavior.[10] Stress and anxiety are widespread among women, with studies showing elevated levels compared to men.[11] Several factors contribute to this gender gap, including societal pressures, hormonal changes, and psychosocial stressors. Women tend to seek help for mental health issues more often than men, resulting in higher reported rates of stress and anxiety among women.[12] This willingness to seek support may be influenced by factors such as greater awareness of mental health, societal encouragement to express emotions, and stronger social support networks.[13] However, despite this tendency, societal stigma surrounding mental health can still prevent some women from seeking help. Cultural norms and gender expectations may pressure women to appear strong and resilient, leading them to hesitate in acknowledging their mental health struggles. Additionally, women from marginalized communities may face intersecting forms of discrimination that further hinder their access to mental health support.[14,15] As a result, there may be under-reporting of stress and anxiety symptoms among women. Addressing societal stigma and promoting gender-sensitive mental health care are crucial in ensuring that all individuals, regardless of gender, feel empowered to seek the support they need for their mental well-being. The 5-stage mindfulness meditation involves counting the breath while focusing on the end and head of each breath, observing the breath's movement throughout the body, noticing the breath around the nose, and cultivating open awareness. While research often focuses on assessing the effects of comprehensive programs like Mindfulness-Based Stress Reduction (MBSR) on anxiety, these programs can be prohibitively expensive and time-intensive.[16] A meta-analysis study investigating the effectiveness of MBSR programs in reducing stress and improving health outcomes revealed valuable insights into the benefits of mindfulness meditation for stress reduction among women, despite also including men in the study.[17] Therefore, it is essential to investigate the impact of individual meditation practices, including their duration, on stress and anxiety levels in women. Objectives: Meditation enhances mental health and helps manage stress and anxiety. Regular meditation sessions can increase tranquility, mental clarity, and emotional resilience. However, the optimal duration for mindfulness meditation needs further investigation. This study examined the impact of a 5-stage mindfulness meditation program, administered for varying durations, on anxiety levels in women without psychiatric diagnoses. Methods: Twenty-five volunteer participants were enrolled and divided into three groups: two experimental groups, which engaged in mindfulness meditation for either 10 minutes or 20 minutes, and a control group that did not meditate. The meditation sessions were conducted over an 8-week period using both a licensed trainer and recorded guidance. Various measures were administered to all groups to assess the outcomes. Results: Both 10-minute and 20-minute meditation interventions were effective compared to pre-intervention. While post-intervention anxiety scores did not significantly differ between the 10-minute and 20-minute groups, both experimental groups exhibited significantly reduced anxiety levels compared to the control group. Similarly, perceived stress scores showed significant reductions in both meditation groups compared to the control group, with no significant differences between the 10-minute and 20-minute groups. Mindfulness scores and intolerance of uncertainty scores did not significantly differ between the meditation groups and the control group post-meditation. Conclusion: This research is expected to contribute to the understanding of the varying effects of different time durations of 5-stage mindfulness meditation on stress-induced anxiety in women. The findings could lead to more accessible and practical mental health interventions, especially for women with limited time and resources.