OBJECTIVE In this study, we aimed to identify patients with PPROM between 24 and 34 weeks of gestation who had high potential for delivery before 72 hours of gestation based on systemic inflammatory parameters. METHODS In this retrospective study, 101 patients with preterm prelabor rupture of membranes (PPROM) between 24 and 34 weeks of gestation were evaluated. Patients were divided into two groups: those who delivered within 72 hours (n = 51) and those who delivered after 72 hours (n = 50). Demographic data, inflammatory markers (NLR, PLR, CRP, fibrinogen), and neonatal outcomes were compared between the groups. Statistical analyses were performed to assess the predictive value of inflammatory markers for delivery within 72 hours. RESULTS Among the inflammatory markers examined, CRP, fibrinogen, NLR, and PLR levels were significantly higher in patients who delivered within 72 hours (p = 0.034, p = 0.015, p = 0.020, and p = 0.028, respectively). In multivariate analysis, cervical dilatation (p = 0.004) and PLR (p = 0.008) were identified as independent predictors of delivery within 72 hours. Cervical dilatation had a specificity of 86.0%, while PLR had a sensitivity of 66.6%, with an AUC of 0.627. CONCLUSION PLR was identified as a moderate predictor for delivery within 72 hours in PPROM cases. However, it should be used in conjunction with other clinical factors to improve decision-making.